Dietary supplementation with curcumin-loaded nanocapsules in lambs: Nanotechnology as a new tool for nutrition
| Autor: | Luiz Gustavo Griss, Hiam Marcon, Carine F. Souza, Marcelo Vedovatto, Matheus D. Baldissera, Aline Ferreira Ourique, Bruno G.O. Cecere, Gabriela M. Galli, Karoline W. Leal, Davi F. Alba, Vitória de Almeida Bassotto, Aleksandro S. Da Silva, Samanta da Silva Gündel, Vitor L. Molosse |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Antioxidant
Globulin medicine.medical_treatment Performance medicine.disease_cause SF1-1100 Nanocapsules Superoxide dismutase 03 medical and health sciences chemistry.chemical_compound Animal science Food Animals medicine Original Research Article Curcuma longa 030304 developmental biology 0303 health sciences Sheep Triglyceride biology Chemistry 0402 animal and dairy science 04 agricultural and veterinary sciences 040201 dairy & animal science Animal culture biology.protein Curcumin Animal Science and Zoology medicine.symptom Anti-inflammatory Weight gain Oxidative stress |
| Zdroj: | Animal Nutrition, Vol 7, Iss 2, Pp 521-529 (2021) Animal Nutrition |
| ISSN: | 2405-6545 |
| Popis: | Curcumin-containing nanocapsule powder formulations have not been used in ruminant feed to date, despite the fact that curcumin is known to be a functional food additive. The objective of this study was to determine whether ethyl polymethacrylate (Eudragit L-100) nanocapsules loaded with curcumin (N-CU) would improve health and growth of lambs. Thirty-two male Lacaune lambs (body weight [BW] = 16 ± 0.99 kg; 45 d of age) were randomly assigned to 1 of 4 treatments: T0, T1, T2 and T4, representing supplementation of curcumin at 0, 1, 2, and 4 mg/kg concentrate, respectively. The animals in each treatment were allocated in 4 pens of 2 lambs each (8 lambs per treatment). The experiment lasted 17 d, with samples and measurements collected on d 0, 7, 12, and 17. The T2 lambs had greater average daily gain than T0 lambs. Regression analysis showed that the ideal dose of N-CU to enhance weight gain was 1.89 mg/kg concentrate. There were significant interactions (P |
| Databáze: | OpenAIRE |
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