Quantum Chemical Study on Mefenamic Acid Polymorphic Forms
| Autor: | Svitlana V. Shishkina, Yevhenii A. Vaksler, Irina S. Konovalova, Victoriya V. Dyakonenko, Victoriya V. Varchenko |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | ACS Omega. 7:17544-17554 |
| ISSN: | 2470-1343 |
| DOI: | 10.1021/acsomega.1c06967 |
| Popis: | Three polymorphic structures of mefenamic acid, which is a very popular drug, have been studied using quantum chemical methods. It has been shown that the centrosymmetric dimer formed due to two O-H···O hydrogen bonds is a complex building unit in all of the polymorphic structures under study. On the basis of an analysis of the pairwise interaction energies between molecules, the polymorphic forms |
| Databáze: | OpenAIRE |
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