Ocular blood flow values measured by laser speckle flowgraphy correlate with the postmenstrual age of normal neonates
| Autor: | Yuuji Katayama, Takashi Itokawa, Norio Mizukaki, Tetsushi Arimura, Yuichi Hori, Kotaro Hine, Tomoaki Shiba, Hitoshi Yoda, Tadashi Matsumoto |
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| Jazyk: | angličtina |
| Předmět: |
Male
medicine.medical_specialty Supine position Optic Disk Optic disk Body weight Pediatrics Optic nerve head Microcirculation 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Reference Values Ophthalmology Laser-Doppler Flowmetry medicine Humans LSFG-baby Laser speckle flowgraphy Postmenstrual age business.industry Body Weight Infant Newborn Postmenstrual Age Retinopathy of prematurity Blood flow Laser Doppler velocimetry medicine.disease Sensory Systems Surgery Ocular blood flow Normal neonate 030221 ophthalmology & optometry Female business Blood Flow Velocity 030217 neurology & neurosurgery |
| Zdroj: | Graefe's Archive for Clinical and Experimental Ophthalmology |
| ISSN: | 0721-832X |
| DOI: | 10.1007/s00417-016-3362-6 |
| Popis: | Purpose To evaluate the relationships between optic nerve head (ONH) blood flow by laser speckle flowgraphy (LSFG), and postmenstrual age and body weight in normal neonates. Methods During their normal sleep, we studied 24 infants (postmenstrual age, 248–295 days) whose ocular blood flow could be measured three consecutive times. While the subjects slept in the supine position, three mean blur rate (MBR) values of the ONH were obtained: the MBR-A (mean of all values), MBR-V (vessel mean) and MBR-T (tissue mean) in the ONH. With regard to eye diseases, no retinopathy of prematurity (ROP) was observed, and no severe systemic diseases requiring treatment were noted in the subjects. Pearson’s correlation coefficients were used to determine the relationship between the MBR-A, −V, −T and postmenstrual age (days) and body weight (g). Results Postmenstrual age was significantly correlated with MBR-A (r = 0.64, p = 0.0007), MBR-V (r = 0.62, p = 0.0012) and MBR-T (r = 0.62, p = 0.0012). However, the body weight was not correlated with the MBR (MBR-A: r = 0.37, p = 0.07, MBR-V: r = 0.31, p = 0.14, MBR-T: r = 0.38, p = 0.06). Conclusions Our results clarified that the values of ocular blood flow measured by LSFG correlate with the postmenstrual age of normal neonates. |
| Databáze: | OpenAIRE |
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