Problem-Solving Therapy Reduces Suicidal Ideation In Depressed Older Adults with Executive Dysfunction

Autor: George S. Alexopoulos, Grace Niu, Kristen A. Gustavson, Charles E. McCulloch, Tanya Meade, Patricia A. Areán
Rok vydání: 2016
Předmět:
Male
Suicide Prevention
Aging
Comparative Effectiveness Research
executive dysfunction
Poison control
Suicide prevention
law.invention
Executive Function
0302 clinical medicine
Randomized controlled trial
law
80 and over
Suicidal ideation
Problem Solving
older adults
Aged
80 and over

Depression
Middle Aged
Serious Mental Illness
Diagnostic and Statistical Manual of Mental Disorders
Suicide
Psychiatry and Mental health
Treatment Outcome
Mental Health
suicide ideation
6.1 Pharmaceuticals
Public Health and Health Services
Female
Cognitive Sciences
medicine.symptom
Psychology
problem-solving therapy
Clinical psychology
Clinical Trials and Supportive Activities
Clinical Sciences
Article
Suicidal Ideation
03 medical and health sciences
Clinical Research
Rating scale
Behavioral and Social Science
medicine
Humans
Aged
Psychiatric Status Rating Scales
Depressive Disorder
Major

Depressive Disorder
030214 geriatrics
Prevention
Major
Evaluation of treatments and therapeutic interventions
Brain Disorders
Psychotherapy
Geriatrics
Supportive psychotherapy
Geriatrics and Gerontology
Cognition Disorders
030217 neurology & neurosurgery
Stroop effect
Executive dysfunction
Zdroj: The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, vol 24, iss 1
ISSN: 1064-7481
Popis: Objective To test the hypothesis that Problem Solving Therapy (PST) is more effective than Supportive Therapy (ST) in reducing suicidal ideation in older adults with major depression and executive dysfunction. We further explored whether patient characteristics, such as age, sex, and additional cognitive impairment load (e.g., memory impairments) were related to changes in suicidal ideation over time. Design Secondary data analysis using data from a randomized clinical trial allocating participants to PST or ST at 1:1 ratio. Raters were blind to patients' assignments. Setting University medical centers. Participants 221 people aged 65 years old and older with major depression determined by Structured Clinical Interview for DSM-III-R diagnosis and executive dysfunction as defined by a score of 33 or less on the Initiation-Perseveration Score of the Mattis Dementia Rating Scale or a Stroop Interference Task score of 25 or less. Interventions 12 weekly sessions of PST or ST. Main Outcome Measures The suicide item of the Hamilton Depression Rating Scale. Results Of the 221 participants, 61% reported suicidal ideation (SI). The ST group had a lower rate of improvement in SI after 12 weeks (44.6%) than did the PST group (60.4%, Fisher's exact test p = 0.031). Logistic regression showed significantly greater reductions in SI in elders who received PST at both 12 weeks (OR: .50, Z = –2.16, p = 0.031) and 36 weeks (OR: 0.5, Z = –1.96, p = 0.05) after treatment. Conclusions PST is a promising intervention for older adults who are at risk for suicide. ClinicalTrials.gov Identifier: NCT00052091
Databáze: OpenAIRE