Detection of Dengue Virus Serotype 3 in Cajamarca, Peru: Molecular Diagnosis and Clinical Characteristics
| Autor: | Sungmin Kym, Victor Zavaleta-Gavidia, Juana del Valle-Mendoza, Daniel Cornejo-Pacherres, Eduardo Verne, Angela Cornejo-Tapia, Jorge Bazán-Mayra, Luis J. del Valle, Wilmer Silva-Caso, Hugo Carrillo-Ng, Ronald Aquino-Ortega, Yordi Tarazona-Castro, Miguel Angel Aguilar-Luis |
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| Přispěvatelé: | Universitat Politècnica de Catalunya. Departament d'Enginyeria Química, Universitat Politècnica de Catalunya. PSEP - Polimers Sintètics: Estructura i Propietats. Polimers Biodegradables |
| Rok vydání: | 2022 |
| Předmět: |
Serotype
Microbiology (medical) Virologia Ciències de la salut::Medicina [Àrees temàtiques de la UPC] Epidemiology diagnosis viruses Ns1 antigen Dengue virus medicine.disease_cause Arbovirus Dengue fever Serology Dengue Virology Diagnosis Peru medicine Epidemiologia DENV business.industry virus diseases Febrile illness Outbreak General Medicine biochemical phenomena metabolism and nutrition medicine.disease arbovirus Infectious Diseases business |
| Zdroj: | Universidad Peruana de Ciencias Aplicadas (UPC) Repositorio Academico-UPC UPC-Institucional Universidad Peruana de Ciencias Aplicadas instacron:UPC Asian Pacific Journal of Tropical Medicine UPCommons. Portal del coneixement obert de la UPC Universitat Politècnica de Catalunya (UPC) |
| ISSN: | 1201-9712 |
| Popis: | Objective: To describe and molecularly characterize an outbreak of dengue virus (DENV) infection in Cajamarca, an Andean region in Peru. Methods: A total of 359 serum samples from patients with acute febrile illness were assessed for the presence of DENV via RT-PCR, ELISA NS1, IgM and IgG in Cajamarca, Peru from January 2017 to June 2017. The evaluation of the different diagnostic tests and their applicability was performed. Results: Dengue virus was detected in 24.7% of samples by RTPCR. Meanwhile, serological analysis detected 30.3% positive cases via ELISA NS1 antigen, 16.7% via ELISA IgG and 9.7% via ELISA IgM. Most of the cases corresponded to DENV-3 (77.5%). The use of RT-PCR performed better in primary infections (P |
| Databáze: | OpenAIRE |
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