Is the volume injected a parameter likely to influence the erectile response observed after intracavernous administration of an alpha-blocking agent?
| Autor: | J F Louis, Françoise Bressolle, B. Sarrazin, Nicolas Mottet, F. Saudubray, Navratil H, Pierre Costa |
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| Rok vydání: | 1993 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Moxisylyte Urology Priapism Injections Erectile Dysfunction medicine Humans Spinal cord injury Spinal Cord Injuries business.industry Penile Erection Significant difference medicine.disease Surgery Solutions medicine.anatomical_structure Alpha blocking Anesthesia Solvents business Penis medicine.drug |
| Zdroj: | European urology. 24(1) |
| ISSN: | 0302-2838 |
| Popis: | In 12 impotent patients with spinal cord injury, we assessed the erectile response induced by intracavernous administration of 20 mg moxisylyte dissolved in 4 different volumes of solvent. We tested successively in each patient 0.4, 0.8, 1.2 ml and the volume usually injected of 2 ml, with a 7-day interval between 2 injections. The reduction in the volume from 2 to 0.4 ml did not thwart the quality of erection obtained by the intracorporeal administration of 20 mg moxisylyte. Indeed, for each erectile parameter (rigidity, abdominopenile angle, length and circumference of the penis), no statistically significant difference arose between the 4 tests. All patients achieved full rigidity. Neither priapism nor prolonged erection occurred. These results suggest that discreet and easily handled small-sized injection pens, containing little solution, could be conceived for autoinjection therapy. |
| Databáze: | OpenAIRE |
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