The effects of smoking on whisker movements: A quantitative measure of exploratory behaviour in rodents
| Autor: | Gina L. J. Galli, Wim Janssens, Hans Degens, Nele Cielen, Karen Maes, Robyn A. Grant, Ghislaine Gayan-Ramirez, Nele Heulens |
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| Rok vydání: | 2016 |
| Předmět: |
Male
0301 basic medicine medicine.medical_treatment Video Recording Physiology Developmental psychology Nicotine Mice 03 medical and health sciences Behavioral Neuroscience chemistry.chemical_compound 0302 clinical medicine medicine Animals Neurotransmitter Lung Compliance Lung function Smoking General Medicine Exploratory behaviour Quantitative measure Alertness 030104 developmental biology chemistry Vibrissae Exploratory Behavior Smoking cessation Anxiety Smoking Cessation Animal Science and Zoology medicine.symptom Psychology Locomotion 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Behavioural Processes. 128:17-23 |
| ISSN: | 0376-6357 |
| Popis: | Nicotine, an important component of cigarette smoke, is a neurotransmitter that contributes to stress, depression and anxiety in smokers. In rodents, it increases anxiety and reduces exploratory behaviours. However, so far, the measurements of exploratory behaviour in rodents have only been semi-quantitative and lacking in sufficient detail to characterise the temporal effect of smoking cessation. As rodents, such as mice and rats, primarily use whiskers to explore their environment, we studied the effect of 3 months smoking with 1 and 2 weeks smoking cessation on whisker movements in mice, using high-speed video camera footage and image analysis. Both protraction and retraction whisker velocities were increased in smoking mice (p |
| Databáze: | OpenAIRE |
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