The interaction of 2,4-dichlorophenoxyacetic acid, ribosomes and polyamines in Azospirillum brasilense
| Autor: | Adriana Fabra, Héctor Balegno, Stella Castro, Gladys Mori, Walter Giordano, Viviana Rivarola |
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| Rok vydání: | 1993 |
| Předmět: |
2
4-Dichlorophenoxyacetic acid DNA synthesis Biogenic Polyamines Azospirillum brasilense Metabolism Ribosomal RNA Biology Toxicology biology.organism_classification Ribosome chemistry.chemical_compound chemistry Biochemistry Protein Biosynthesis Protein biosynthesis 2 4-Dichlorophenoxyacetic Acid Polyamine Ribosomes |
| Zdroj: | Toxicology. 83:19-29 |
| ISSN: | 0300-483X |
| DOI: | 10.1016/0300-483x(93)90088-a |
| Popis: | 2,4-Dichlorophenoxyacetic acid (2,4-D) is an herbicide used extensively in agriculture. We had previously determined that 1 mM 2,4-D could inhibit cell growth, DNA and protein synthesis of Azospirillum brasilense. The present work was designed to determine if these alterations are a consequence of 2,4-D action on polyamine biosynthesis and if the protein synthesis inhibition is a result of ribosomal impairment. In this paper we demonstrate that 2,4-D alters the metabolism of polyamines and, thus, affects protein synthesis at the ribosomal level. |
| Databáze: | OpenAIRE |
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