Autologous Adipose Tissue Injection of Vocal Cords in Presbyphonia

Autor: Andrés Navarro-Mediano, Guillermo Plaza, Estefanía Hernández-García, Ramón González-Herranz
Rok vydání: 2021
Předmět:
Zdroj: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 167(1)
ISSN: 1097-6817
Popis: This series evaluates the long-term results of autologous adipose injection (AAI) in patients older than 65 years with presbyphonia.Retrospective cohort study.Academic secondary medical center.This was a retrospective study with a minimum follow-up of 12 months. All patients underwent AAI for atrophy of both vocal folds due to presbyphonia. We measured subjective parameters as Voice Handicap Index-10 (VHI-10) or GRBAS scale (grade, roughness, breathiness, asthenia, strain) and objective measures such as maximum phonation time (MPT) or square pixel closure defect. We reviewed the medical records of patients undergoing AAI during the 2011-2018 period. An analysis of the demographic variables of the group was performed, as well as the values of VHI-10, GRBAS, and MPT, and the minimum closure defect measured in square pixels and the number of closed frames in the glottal cycle before and after the intervention.At 12 months, 17 of 18 patients reported subjective and VHI-10 improvement. The mean preoperative VHI-10 (26.7) was significantly higher than the postoperative value (14.4), and the GRBAS scale had a preoperative mean of 8.7 and a postoperative mean of 4.3, both with statistical significance. MPT increased from 7.7 to 12.4 seconds (AAI improves long-term vocal fold closure, demonstrating utility in patients with presbyphonia.
Databáze: OpenAIRE