Functional and traditional training improve muscle power and reduce proinflammatory cytokines in older women: A randomized controlled trial

Autor: Alan Bruno Silva Vasconcelos, Otávio de Toledo Nóbrega, José Carlos Aragão-Santos, Gleiciane Gontijo Avelar, Marzo Edir Da Silva-Grigoletto, Enilton A. Camargo, Albernon Costa Nogueira, Gilberto Santos Morais Junior, Marcos Raphael Pereira Monteiro, Antônio Gomes de Resende-Neto
Rok vydání: 2020
Předmět:
Zdroj: Experimental Gerontology. 135:110920
ISSN: 0531-5565
DOI: 10.1016/j.exger.2020.110920
Popis: Background Aging is a natural process that, even in the nonattendance of complex diseases, is associated with a numerous behavioral change that attributes reduced muscle mass, power, strength and function. In addition, aging linked to low-grade inflammatory status, characterized by increased plasma concentrations of inflammatory cytokines such as TNF-α and IL-6. Physical exercise is the main non-pharmacological strategy for improving the physical fitness of the aged individuals. However, it is still controversial whether exercise can reduce aging-mediated inflammation. Objective To analyze the effects of functional (FT) and traditional (TT) training practice on muscle power and inflammatory profile in physically active older women. Methods The study has been performed for twenty-six weeks in which twenty-four weeks utilized for training sessions and two weeks for physical and biochemical assessments. Forty-three older women (age FT: 64.25 ± 4.70, range: 60–75; TT: 64.90 ± 3.03, range: 60–71; Control: 65.91 ± 5.79, range: 60–75) were randomly divided into three groups: Functional (FT; n = 16); Traditional (TT; n = 16) training groups; and Control Group (CG; n = 11) respectively. Muscle power tests were performed by push (Bench press) and squatting (Squat) actions. The jumping ability was performed through Counter Movement Jump (CMJ). In addition, isometric strength were assessed by Hand Grip Test. Plasma cytokine concentration was measured using flow cytometry. Results Functional and traditional training sessions subjected to aged women demonstrated a significant enhancement in their physical activity and muscle power. The trained individuals from above two groups showed significant improvements in all analyzed parameters excluding hand-grip. Functional and traditional training exercise reduced the plasma concentrations of TNF-α (FT: p = 0.0001; TT: p = 0.0410) and whereas FT group has reduced IL-6 (p = 0.0072), but did not affect the alterations of pre and post measurements of IL-2 (FT: p = 0.0651; TT: p = 0.2146) and IL-10 values (FT: p = 0.2658; TT: p = 0.3116). There was no significant difference in any of the test parameters between FT and TT groups. Conclusion The functional and traditional training practices showed equivalent beneficial outcomes by increasing muscle power and reducing systemic markers associated with inflammation.
Databáze: OpenAIRE
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