Transcatheter Oily Chemoembolization of the Inferior Phrenic Artery in Hepatocellular Carcinoma: The Safety and Potential Therapeutic Role
| Autor: | Jin Wook Chung, Tae-Kyung Kim, Joon Koo Han, Jae Hyung Park, Man Chung Han, Byung Ihn Choi |
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| Rok vydání: | 1998 |
| Předmět: |
Adult
Male medicine.medical_specialty Carcinoma Hepatocellular medicine.medical_treatment Contrast Media Mitomycins Hepatic Artery medicine.artery Antineoplastic Combined Chemotherapy Protocols medicine Humans Radiology Nuclear Medicine and imaging Embolization Chemoembolization Therapeutic skin and connective tissue diseases Aged Retrospective Studies business.industry Liver Neoplasms Iodized Oil Middle Aged Inferior phrenic arteries bacterial infections and mycoses medicine.disease Gelatin Sponge Absorbable Empyema respiratory tract diseases Surgery Survival Rate medicine.anatomical_structure Doxorubicin Hepatocellular carcinoma Transcatheter oily chemoembolization Female Radiology Cardiology and Cardiovascular Medicine business Intercostal arteries Artery Liver abscess |
| Zdroj: | Journal of Vascular and Interventional Radiology. 9:495-500 |
| ISSN: | 1051-0443 |
| DOI: | 10.1016/s1051-0443(98)70306-9 |
| Popis: | Purpose To evaluate the efficacy and safety of transcatheter oily chemoembolization therapy (TOCE) via the inferior phrenic artery (IPA) in hepatocellular carcinoma (HCC). Materials and Methods Fifty patients with HCC underwent a total of 82 procedures of TOCE of the IPA, as well as of the hepatic artery. In 16 patients, additional extrahepatic collaterals were depicted and were also embolized in 10 patients. TOCE was performed with an emulsion of iodized oil and doxorubicin hydrochloride, and gelatin sponge particle embolization was added in 32 patients. Results Initial response showed complete or partial remission of the tumor in 31 patients. The cumulative survival rates after combined TOCE of the hepatic artery, IPA, and other extrahepatic arteries were 89% (6 months), 78% (1 year), 46% (2 year), and 30% (3 year), when calculated from the time of IPA chemoembolization. Liver abscess and empyema developed in one case of combined IPA and multiple intercostal artery chemoembolization. There were no serious complications after IPA chemoembolization alone. Conclusion TOCE of the IPA has a potential therapeutic role as a safe adjunct to TOCE of the hepatic artery in the management of HCC supplied by the IPA. |
| Databáze: | OpenAIRE |
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