The comparison of manual vs automated disc margin delineation using spectral-domain optical coherence tomography
| Autor: | Mitra Sehi, Shawn M Iverson |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty genetic structures Coefficient of variation Optic Disk Nerve fiber layer Glaucoma Spectral domain Diagnostic Techniques Ophthalmological chemistry.chemical_compound Quadrant (abdomen) Nerve Fibers Optical coherence tomography Ophthalmology medicine Humans Prospective Studies Aged Analysis of Variance medicine.diagnostic_test business.industry Retinal Middle Aged medicine.disease eye diseases medicine.anatomical_structure Concordance correlation coefficient chemistry Case-Control Studies Clinical Study Female sense organs business Tomography Optical Coherence |
| Zdroj: | Eye. 27:1180-1187 |
| ISSN: | 1476-5454 0950-222X |
| DOI: | 10.1038/eye.2013.163 |
| Popis: | To examine the impact of manual vs automated disc margin delineation on optic nerve head (ONH) and retinal nerve fiber layer (RNFL) parameters using spectral-domain optical coherence tomography (SDOCT). A prospective cohort study consisting of normal, glaucoma suspect (GS) and glaucoma patients who underwent ONH and RNFL measurements using SDOCT technology (RTVue; Optovue Inc.). The retinal pigment epithelium/Bruch’s membrane (RPE/BM) complex end points were automatically determined first, and were manually redefined subsequently. Analysis of variance, coefficient of variation (COV), concordance correlation coefficient (CCC), and Bland–Altman plots were used for the analyses. Ninety-nine eyes of 50 subjects (age 68±10 years) consisting of 36 glaucoma, 56 GS, and 7 normal eyes were included. The RNFL thickness measurements were similar (P>0.05) between the two methods of demarcation, except for the inferior-nasal sector (P=0.04). For the ONH measurements, the cup-to-disc (C/D) ratio and rim area showed significant differences between the two methods (P |
| Databáze: | OpenAIRE |
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