Encapsulated bacteria deform lipid vesicles into flagellated swimmers
| Autor: | Lucas Le Nagard, Aidan T. Brown, Angela Dawson, Vincent A. Martinez, Wilson C. K. Poon, Margarita Staykova |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
cond-mat.soft
Multidisciplinary Flagella/physiology Escherichia coli/cytology Cytoplasmic Vesicles FOS: Physical sciences Membranes Artificial Condensed Matter - Soft Condensed Matter Cytoplasmic Vesicles/microbiology Lipids Flagella Biological Physics (physics.bio-ph) Artificial Cells/microbiology physics.bio-ph Escherichia coli Soft Condensed Matter (cond-mat.soft) Artificial Cells Physics - Biological Physics |
| Zdroj: | Proceedings of the National Academy of Sciences, 2022, Vol.119(34) [Peer Reviewed Journal] Nagard, L L, Brown, A T, Dawson, A, Martinez, V A, Poon, W C K & Staykova, M 2022, ' Encapsulated bacteria deform lipid vesicles into flagellated swimmers ', Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 34, e2206096119, pp. 1-7 . https://doi.org/10.1073/pnas.2206096119 |
| Popis: | We study a synthetic system of motile Escherichia coli bacteria encapsulated inside giant lipid vesicles. Forces exerted by the bacteria on the inner side of the membrane are sufficient to extrude membrane tubes filled with one or several bacteria. We show that a physical coupling between the membrane tube and the flagella of the enclosed cells transforms the tube into an effective helical flagellum propelling the vesicle. We develop a simple theoretical model to estimate the propulsive force from the speed of the vesicles, and demonstrate the good efficiency of this coupling mechanism. Together, these results point to design principles for conferring motility to synthetic cells. 22 pages, 12 figures |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|