Effects of individual self-management education on clinical, biological, and adherence outcomes in asthma
| Autor: | Steven M. Paul, Jack K. Covington, Homer A. Boushey, Susan L. Janson, John V. Fahy, Warren M. Gold |
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| Rok vydání: | 2003 |
| Předmět: |
Adult
Male medicine.medical_specialty Randomization Health Behavior law.invention Quality of life Randomized controlled trial Patient Education as Topic law Adrenal Cortex Hormones Internal medicine Intervention (counseling) Administration Inhalation medicine Humans Prospective Studies Asthma Inflammation Self-management business.industry Sputum General Medicine medicine.disease Respiratory Function Tests Clinical trial Eosinophils Self Care Outcome and Process Assessment Health Care Treatment Outcome Physical therapy Patient Compliance Female medicine.symptom business Biomarkers |
| Zdroj: | The American journal of medicine. 115(8) |
| ISSN: | 0002-9343 |
| Popis: | Background Asthma guidelines urge teaching patients the knowledge and skills required for self-management, based on the assumption that education will lead to improved skills and better asthma control. Methods In a prospective, randomized controlled trial of 65 adults with mild-to-moderate asthma, we examined whether an educational self-management intervention would improve adherence to inhaled corticosteroid therapy, decrease markers of airway inflammation, and improve clinical control. Peak flow, symptoms, and adherence were monitored for 7 weeks. After a 1-week run-in, subjects were assigned randomly to either the educational intervention or control group. The 30-minute intervention was delivered and reinforced at biweekly intervals. Results Compared with the control group, the intervention group had improvements in adherence to inhaled corticosteroid therapy (by 30% vs. −5%, P = 0.01), self-reported control of asthma (by 14% vs. 5%, P = 0.04), and perhaps quality of life (by 37% vs. 21%, P = 0.06). The direction of change for all other clinical outcomes was more favorable in the intervention group, but not significantly so. Markers of inflammation in sputum decreased more in the intervention group, with sputum eosinophils declining significantly ( P = 0.02). Conclusion In asthmatic patients treated with inhaled corticosteroids, education and training in self-management improves adherence with inhaled therapy, perceived control of asthma, and sputum eosinophilia. |
| Databáze: | OpenAIRE |
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