| Autor: |
Shrivastava, Asha, Namit Garg, Dave, Rashmi |
| Jazyk: |
angličtina |
| Rok vydání: |
2013 |
| Předmět: |
|
| DOI: |
10.5281/zenodo.4483066 |
| Popis: |
The patients withtype 2 diabetes mellitus(T2DM) are at high risk for future cardiovascular events. The present study was aimed to assess the future 8 year diabetic and 10 year cardiovascular risk in first degree relatives of T2DMand association with glycemic status as measured by Fasting plasma glucose (FPG) and glycosylated haemoglobin (A1c) levels. Method: Out of 230 first degree relatives of T2DM patients attending the diabetic clinic of Hamidia hospital ,60 subjects having FPG in prediabetic rangeand 60 age and sex matched (30-60 yrs) normoglycemics healthy controls were selected . FPG, A1cand lipid profile were measured as per the standard laboratory Method. Prediabetes and T2DM was defined as per American Diabetes Association criteria (2011) and dyslipidemia was defined as per NCEP ATP III guidelines (2004). Future diabetic and cardiovascular risk were assessed by using Framingham Risk Score (2007) and Framinghamcardiovascular risk score (2008) Result: Dyslipidemia was identified in 32 % of prediabetics.Overall diabetic and cardiovascular risk in prediabetic group was found to be 23.13 ± 9.85 % and 10.85± 9.19 % respectively. Dyslipidemia was associated with 26.28 ±8.65% diabetic and 12.88±9.98% cardiovascular risk.FPG and A1c showed positive correlation with future diabetic risk(r=0.55,0.61) and cardiovascular risk(r=0.49,0.73).Conclusion:It is concluded that A1c levels below the threshold for diagnosis of diabetes( |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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