Multicentre study of fragrance allergy in Hungary
| Autor: | Attila Horváth, Rita Judák, Sándor Husz, Valéria Kohánka, László Nebenführer, Csilla Mészáros, Erzsébet Temesvári, Ilona Németh, Éva Remenyik, Mátyás J. Baló-Banga, Andrea Szegedi, Zsuzsa Somos |
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| Rok vydání: | 2002 |
| Předmět: |
Adult
Male medicine.medical_specialty Allergy Adolescent Dermatology medicine.disease_cause chemistry.chemical_compound Sex Factors Allergen medicine Humans Immunology and Allergy Child Sensitization Hungary Hydroxycitronellal business.industry Age Factors Patch test Allergens Middle Aged Patch Tests medicine.disease Perfume Isoeugenol medicine.anatomical_structure chemistry Delayed hypersensitivity Dermatitis Allergic Contact Female business Contact dermatitis |
| Zdroj: | Contact Dermatitis. 46:325-330 |
| ISSN: | 0105-1873 |
| Popis: | The authors followed the frequency of fragrance contact sensitization in Hungary in a multicentre study in the years 1998 and 1999. A total of 3,604 patients were tested with fragrance mix (FM), and positive reactions were observed in 294 (8.2%). In 160 FM hypersensitive patients, the study was continued with patch testing of the mix constituents (cinnamic alcohol, cinnamic aldehyde, eugenol, amyl cinnamic aldehyde, hydroxycitronellal, geraniol, isoeugenol, oak moss absolute). Of the patients tested, 70.6% produced positive reactions to the constituents. FM contact sensitization was mainly observed in female patients (74.4%). The incidence of contact urticaria in FM hypersensitive patients was 6.1%. Simultaneous patch test trials of other environmental contact allergens, in both early and late evaluations, mainly confirmed hypersensitivity reactions to balsams. Female dominance of hypersensitivity reactions observed during testing the individual components of the mix was striking (82.4%). In positive skin reactions, cinnamic alcohol, isoeugenol and oak moss provoked skin symptoms most frequently. We also tested the 104 patients who produced negative reactions to FM with the constituent individual allergens, with 11.9% positive incidence. The clinical symptoms of the patients were above all manifest in the form of contact eczema, located on the hands, face, eyelids and axillae. With this study, the authors, members of the Hungarian Contact Dermatitis Research Group, call attention to one of the most frequent allergens in the environment. |
| Databáze: | OpenAIRE |
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