Androgen receptor distribution in the social decision-making network of eusocial naked mole-rats
| Autor: | Sharry L. Goldman, Bruce D. Goldman, Nancy G. Forger, Spencer van Mil, Melissa M. Holmes, Camila Bulkowski |
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| Rok vydání: | 2013 |
| Předmět: |
Male
Photomicrography medicine.medical_specialty Decision Making Cell Count Hierarchy Social Biology Behavioral Neuroscience Internal medicine Mole medicine Social decision making Animals Naked mole-rat Sex Characteristics Mole Rats Brain biology.organism_classification Eusociality Immunohistochemistry Breed Androgen receptor Preoptic area Endocrinology Receptors Androgen Female Social status |
| Zdroj: | Behavioural brain research. 256 |
| ISSN: | 1872-7549 |
| Popis: | Naked mole-rats are highly social rodents that live in large groups and exhibit a strict reproductive and social hierarchy. Only a few animals in each colony breed; the remainder are non-reproductive and are socially subordinate to breeders. We have examined androgen receptor immunoreactive (AR+) cells in brain regions comprising the recently described social decision-making network in subordinate and breeder naked mole-rats of both sexes. We find that subordinates have a significantly higher percentage of AR+ cells in all brain regions expressing this protein. By contrast, there were no significant effects of sex and no sex-by-status interactions on the percentage of AR+ cells. Taken together with previous findings, the present data complete a systematic assessment of the distribution of AR protein in the social decision-making network of the eusocial mammalian brain and demonstrate a significant role for social status in the regulation of this protein throughout many nodes of this network. |
| Databáze: | OpenAIRE |
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