Sitostanetriol is not formed in vivo from sitosterol in the rat
| Autor: | Catherine Cordelet, Pierre Juanéda, Lucy Martine, André Grandgirard |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Analysis of Variance
Embryology Chromatography Gas Phytosterol Phytosterols Medicine (miscellaneous) Biology Sitosterols Gas Chromatography-Mass Spectrometry Rats Random Allocation Reproductive Medicine Biochemistry In vivo Human plasma Animals Animal Science and Zoology Food science Rats Wistar Oxidation-Reduction Triglycerides Developmental Biology Food Science |
| Zdroj: | Reproduction Nutrition Development. 44:609-616 |
| ISSN: | 1297-9708 0926-5287 |
| Popis: | In a recent study, we observed some oxyphytosterols in the plasma of healthy human subjects. This experiment was effected in order to determine if these compounds could be formed in vivo from phytosterols. Rats were fed with a high level of phytosterols (1% of the diet) and they were compared to rats deprived of phytosterols, using triglycerides purified from phytosterols. Their plasma were analysed for the main oxyphytosterols. The results show that sitostanetriol and campestanetriol were not formed in vivo from phytosterols. Their levels decreased during the experiment. The diet origin is highly probable for the compounds identified in human plasma. In particular, it seems that the sitostanetriol is eliminated very slowly from the organism. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|