Sequence analysis of the cleavage site-encoding region of the fusion protein gene of Newcastle disease viruses from India and Nepal

Autor:	T. Nanthakumar, G. Butchaiah, Ranjit S. Kataria, A. K. Tiwari, J.M. Kataria, P. P. Goswami
Rok vydání:	2000
Předmět:	Genetics chemistry.chemical_classification General Immunology and Microbiology biology Sequence analysis biology.organism_classification Cleavage (embryo) Newcastle disease Virology Fusion protein Virus Amino acid Food Animals chemistry Animal Science and Zoology Peptide sequence Gene
Zdroj:	Avian Pathology. 29:603-607
ISSN:	1465-3338 0307-9457
DOI:	10.1080/713651205
Popis:	Five field isolates of Newcastle disease virus, including one from a pigeon from the Indian subcontinent, along with three vaccine strains have been characterized by sequence analysis of the fusion protein (F) gene in the region encoding the F 2 -F 1 cleavage site. Based on the amino acid sequence present at the cleavage site and on the percent divergence at nucleotide and amino acid levels, three field isolates could be classified as velogenic and two were of lentogenic pathotypes. The velogenic pathotypes had the sequence RRQK/RRF at the cleavage site, while the lentogenic strains had GRQA/GRL at the corresponding position.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b57ce0f8b21e89b460585f42eced4b7d https://doi.org/10.1080/713651205 Zobrazit plný text záznamu Plný text ve formátu PDF