Screening of Oral Potentially Malignant Disorders Using Exfoliative Cytology: A Diagnostic Modality
| Autor: | Uday Ginjupally, Tanya Khaitan, Debarati Bhowmick, Arpita Kabiraj, Kushal Chatterjee, Aritri Bir |
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| Rok vydání: | 2016 |
| Předmět: |
Pathology
medicine.medical_specialty Article Subject Epidemiology Papanicolaou stain lcsh:Medicine 03 medical and health sciences 0302 clinical medicine stomatognathic system Biopsy Genetics medicine Exfoliative cytology Mass screening Leukoplakia medicine.diagnostic_test business.industry lcsh:R Public Health Environmental and Occupational Health 030206 dentistry medicine.disease Dermatology Oral leukoplakia stomatognathic diseases Oral submucous fibrosis 030220 oncology & carcinogenesis Oral lichen planus business Research Article |
| Zdroj: | Journal of Cancer Epidemiology Journal of Cancer Epidemiology, Vol 2016 (2016) |
| ISSN: | 1687-8558 |
| Popis: | Objective. Oral exfoliative cytology (OEC) has been implemented in the diagnosis of pathologic lesions for ages. The present study was undertaken to evaluate the cytomorphological features of some of the commonest potentially malignant disorders (leukoplakia, lichen planus, and oral submucous fibrosis) through a simple procedure and illustrate its importance in mass screening.Materials and Method. A total of 160 subjects with 25–50 years of age were included in the study. Among them, 40 were clinically diagnosed with oral leukoplakia, 40 were diagnosed with oral lichen planus, 40 were diagnosed with oral submucous fibrosis, and 40 were in the control group. The prepared smears were subjected to Papanicolaou stain and analyzed microscopically for the evaluation of the cytomorphological features.Results and Discussion. When analyzed microscopically, 36 (90%) out of the 40 oral leukoplakic lesions showed Class II cytological features whereas 4 (10%) revealed Class I features. Among 40 patients with oral lichen planus, 26 (65%) showed Class II features while the remaining 14 (35%) revealed Class I features. In 40 subjects with oral submucous fibrosis, 32 (80%) showed Class II features while the other 8 (20%) showed Class I features. All the 40 control subjects showed Class I features. Thus, OEC can be widely advocated as an addition to clinical conclusion and an adjunct to biopsy. |
| Databáze: | OpenAIRE |
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