Genome-Wide Analysis of Nutrient Signaling Pathways Conserved in Arbuscular Mycorrhizal Fungi
Autor: | Xiaoning Fan, Jiangyong Li, Xiaoqin Zhou, Ming Tang, Nianwu Tang, Hongyun Xie, Hui Chen, Xianan Xie |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
0106 biological sciences
0301 basic medicine Microbiology (medical) QH301-705.5 Trehalase activity arbuscular mycorrhizal fungi Nutrient sensing PHO Biology 01 natural sciences Microbiology Article 03 medical and health sciences Symbiosis arbuscule longevity Virology Spore germination Biology (General) Protein kinase A cAMP/PKA Gene Appressorium fungi TOR Cell biology nutrient signaling pathways 030104 developmental biology SNF1 Signal transduction 010606 plant biology & botany appressorium formation |
Zdroj: | Microorganisms, Vol 9, Iss 1557, p 1557 (2021) Microorganisms Volume 9 Issue 8 |
ISSN: | 2076-2607 |
Popis: | Arbuscular mycorrhizal (AM) fungi form a mutualistic symbiosis with a majority of terrestrial vascular plants. To achieve an efficient nutrient trade with their hosts, AM fungi sense external and internal nutrients, and integrate different hierarchic regulations to optimize nutrient acquisition and homeostasis during mycorrhization. However, the underlying molecular networks in AM fungi orchestrating the nutrient sensing and signaling remain elusive. Based on homology search, we here found that at least 72 gene components involved in four nutrient sensing and signaling pathways, including cAMP-dependent protein kinase A (cAMP-PKA), sucrose non-fermenting 1 (SNF1) protein kinase, target of rapamycin kinase (TOR) and phosphate (PHO) signaling cascades, are well conserved in AM fungi. Based on the knowledge known in model yeast and filamentous fungi, we outlined the possible gene networks functioning in AM fungi. These pathways may regulate the expression of downstream genes involved in nutrient transport, lipid metabolism, trehalase activity, stress resistance and autophagy. The RNA-seq analysis and qRT-PCR results of some core genes further indicate that these pathways may play important roles in spore germination, appressorium formation, arbuscule longevity and sporulation of AM fungi. We hope to inspire further studies on the roles of these candidate genes involved in these nutrient sensing and signaling pathways in AM fungi and AM symbiosis. |
Databáze: | OpenAIRE |
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