Movement Disorder-Childhood Rating Scale: A Sensitive Tool to Evaluate Movement Disorders
| Autor: | Giuseppina Sgandurra, Giovanni Cioni, Roberta Battini, Domenico M. Romeo, Ilaria Olivieri, Roberta Di Pietro, Manuela Casarano |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Movement disorders Scale (ratio) Adolescent MD-CRS Severity of Illness Index Pediatrics Correlation Cohort Studies symbols.namesake Physical medicine and rehabilitation Child Development Settore MED/39 - NEUROPSICHIATRIA INFANTILE Developmental Neuroscience Rating scale medicine Humans Psychiatry Child cerebral palsy Movement Disorders movement disorders treatment Univariate Repeated measures design Infant Perinatology and Child Health Bonferroni correction Treatment Outcome movement disorders assessment tool Neurology Child Preschool Pediatrics Perinatology and Child Health Cohort symbols Female movement disorder Neurology (clinical) medicine.symptom pediatric movement disorder Psychology Follow-Up Studies |
| Popis: | Background The Movement Disorder-Childhood Rating Scale represents a new tool for assessment of movement disorders during developmental age. In this study, we evaluated a cohort of 68 patients affected by various types of movement disorders and treated with specific drugs over one year to verify the usefulness of the Movement Disorder-Childhood Rating Scale. Method The participants were divided into two groups according to their ages (0-3 years; 4-18 years) and were evaluated using Movement Disorder-Childhood Rating Scale 0-3 or 4-18 at baseline (i.e., before starting pharmacological treatment [T0], after 6 months [T1], and after 12 months [T2] of treatment. Univariate repeated measures analysis of variance with a Greenhouse-Geisser correction by SPSS 20 was performed to analyze the scale responsiveness for the three indices (e.g., Index I, Index II, Global Index) in each group with time (T0, T1, and T2). In addition, the Bonferroni test was performed to identify the source of significant differences among means. Results Significant differences were found between time points (T1 versus T0, T2 versus T0, and T2 versus T1) in both scales for all indexes with the exception for T2 versus T1 for Index II in both scales and for T2 versus T1 for the Global Index in the older age group. There was no significant correlation between observed changes in the scores and the age of the children, either for Movement Disorder-Childhood Rating Scale 0-3 or 4-18. Conclusion Our results suggest that Movement Disorder-Childhood Rating Scale is a suitable tool to detect changes independently from age and could be used as outcome measure for clinical trials. |
| Databáze: | OpenAIRE |
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