Visualization of changes in the foveal avascular zone in both observed and treated diabetic macular edema using optical coherence tomography angiography

Autor: Jay S. Duker, Andre J. Witkin, Talisa E de Carlo, Caroline R. Baumal, Eduardo A. Novais, Ricardo N. Louzada, Nadia K. Waheed, Aditya Gill, Emily Cole
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: International Journal of Retina and Vitreous, Vol 3, Iss 1, Pp 1-11 (2017)
International Journal of Retina and Vitreous
ISSN: 2056-9920
DOI: 10.1186/s40942-017-0074-y
Popis: Background Central vision loss in diabetic retinopathy is commonly related to diabetic macular edema (DME). The objective of this study was to describe changes between consecutive visits on optical coherence tomography angiography (OCTA) of the foveal avascular zone (FAZ) in eyes with DME. Methods 20 eyes from 14 patients with DME were imaged on 2 successive clinic visits separated by at least 1 month. The mean interval between visits was 3.2 months. The only intervention used was intravitreal anti-VEGF in 11 eyes; the others were observed over time without treatment. Two different readers measured FAZ area using a pseudo-automated tool in comparison to a manual tracing tool. Qualitative changes in the appearance of the vasculature surrounding the FAZ were also recorded. The retinal capillary plexus was segmented into deep and superficial plexuses, and FAZ measurements were done on the superficial, deep, and summated plexuses. Results Pseudo-automated and manual measurements of FAZ area decreased significantly (p
Databáze: OpenAIRE
Externí odkaz: