Morphology and therapeutic chances of interstitial lung disease
| Autor: | I. Mieth, H. Otto |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Pulmonary and Respiratory Medicine
Adult Male Pathology medicine.medical_specialty Adolescent Sarcoidosis Biopsy Pulmonary Fibrosis Lung biopsy Medicine Humans Interstitial pneumonia Lung Aged business.industry Fibrosing alveolitis Lung fibrosis Interstitial lung disease respiratory system Middle Aged medicine.disease respiratory tract diseases Steroid therapy Female Steroids business Alveolitis Extrinsic Allergic |
| Zdroj: | Respiration; international review of thoracic diseases. 38(3) |
| ISSN: | 0025-7931 |
| Popis: | 101 cases of idiopathic interstitial lung disease diagnosed by lung biopsy, were reviewed according to clinical and X-ray appearance and especially to their response to steroid therapy. Four morphological inflammatory reactions are distinguished: (1) alveolitis; (2) onion-like mesenchymal proliferation; (3) sarcoid-like lesions, and (4) lymphofollicular reactions. Especially type 1 and/or type 2 show immediate response to steroid therapy. Only a few cases showed spontaneous improvement. Once a fibrosis exists, a 'restitutio ad integrum' cannot be expected any where. From this group of idiopathic interstitial lung diseases the conclusion seems to be justified that also other types of interstitial lung reactions should be treated with steroids to avoid it turning into lung fibrosis. |
| Databáze: | OpenAIRE |
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