A Simple Analytical Model for Predicting the Detectable Ion Current in Ion Mobility Spectrometry Using Corona Discharge Ionization Sources
| Autor: | Stefan Zimmermann, Ansgar T. Kirk, Tim Kobelt, Hauke Spehlbrink |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Spectrometer
Ion-mobility spectrometry Chemistry 010401 analytical chemistry ddc:621 3 Ion current Ion mobility spectrometry Dewey Decimal Classification::600 | Technik::620 | Ingenieurwissenschaften und Maschinenbau::621 | Angewandte Physik::621 3 | Elektrotechnik Elektronik 010402 general chemistry 01 natural sciences Corona Analytical model Ion source High kinetic energy ion mobility spectrometry 0104 chemical sciences Ion Physics::Plasma Physics Structural Biology Ionization Atomic physics Nuclear Experiment Spectroscopy Corona discharge |
| Zdroj: | Journal of The American Society for Mass Spectrometry 28 (2018), Nr. 7 |
| DOI: | 10.15488/4401 |
| Popis: | Corona discharge ionization sources are often used in ion mobility spectrometers (IMS) when a non-radioactive ion source with high ion currents is required. Typically, the corona discharge is followed by a reaction region where analyte ions are formed from the reactant ions. In this work, we present a simple yet sufficiently accurate model for predicting the ion current available at the end of this reaction region when operating at reduced pressure as in High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) or most IMS-MS instruments. It yields excellent qualitative agreement with measurement results and is even able to calculate the ion current within an error of 15%. Additional interesting findings of this model are the ion current at the end of the reaction region being independent from the ion current generated by the corona discharge and the ion current in High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) growing quadratically when scaling down the length of the reaction region. The final publication is available at Springer via https://doi.org/10.1007/s13361-018-1970-6. |
| Databáze: | OpenAIRE |
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