Complete Genome Sequence of a Novel Bovine Norovirus: Evidence for Slow Genetic Evolution in Genogroup III Genotype 2 Noroviruses
| Autor: | Dominique Ziant, Alexandra Scipioni, Georges Daube, Axel Mauroy, Elisabeth Mathijs, Etienne Thiry |
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| Rok vydání: | 2012 |
| Předmět: |
Genes
Viral Genotype Sequence analysis viruses Molecular Sequence Data Immunology Genome Viral Biology medicine.disease_cause Microbiology Genome Evolution Molecular Open Reading Frames Virology Databases Genetic medicine Animals Gene Genetics Whole genome sequencing Strain (biology) Norovirus Sequence Analysis DNA Genome Announcements Hypervariable region Insect Science DNA Viral Cattle |
| Zdroj: | Journal of Virology. 86:12449-12450 |
| ISSN: | 1098-5514 0022-538X |
| DOI: | 10.1128/jvi.02251-12 |
| Popis: | A new genogroup III genotype 2 bovine norovirus, B309/2003/BE, was entirely sequenced and genetically compared to the original Newbury2/1976/UK strain and to Dumfries/1994/UK, detected in 1976 and 1994, respectively. Interestingly, except in well-defined coding regions (N-terminal protein, 3A-like protease, hypervariable region of the capsid protein, and C-terminal part of the minor structural protein), very low genetic differences were noted between the entire genomes of these three strains along a 30-year-long period. It allowed some hypotheses of hotspots of genetic evolution through a low genetic evolution background in genotype 2 genogroup III bovine noroviruses. |
| Databáze: | OpenAIRE |
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