A laboratory study of an inactivated bivalent iron restricted Salmonella enterica serovars Enteritidis and Typhimurium dual vaccine against Typhimurium challenge in chickens
| Autor: | S. W. Cooles, Martin J. Woodward, M. Breslin, S. Houghton, Lindsay M. Venables, K. A. Sprigings, Felicity A. Clifton-Hadley |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Serotype
Salmonella typhimurium Salmonella Salmonella Vaccines Salmonella enteritidis Iron Colony Count Microbial Enzyme-Linked Immunosorbent Assay medicine.disease_cause Microbiology Statistics Nonparametric Random Allocation Cloaca medicine Animals Poultry Diseases General Veterinary biology Inoculation Vaccination General Medicine biology.organism_classification Virology Enterobacteriaceae Antibodies Bacterial Salmonella enterica biology.protein Female Antibody Chickens |
| Zdroj: | Veterinary microbiology. 89(2-3) |
| ISSN: | 0378-1135 |
| Popis: | A commercial inactivated iron restricted Salmonella Typhimurium and Salmonella Enteritidis vaccine was used to vaccinate chicks at 1 day and again at 4 weeks of age, with challenge by a high and a low dose of S. Typhimurium given either orally or by contact with seeder birds inoculated orally with a high dose of S. Typhimurium. In all three challenge regimes, the shedding of challenge strain was reduced significantly (p < 0.05) in vaccinated birds compared with unvaccinated controls. Vaccination reduced colonisation of internal organs after challenge by contact seeder birds. However, no effect of vaccination upon colonisation of internal organs after either high or low oral challenge was apparent. In conclusion, the data indicate that the vaccine should be a useful tool in the control of S. Typhimurium infection in chickens. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect