Use of micro computed-tomography and 3D printing for reverse engineering of mouse embryo nasal capsule
| Autor: | David Paloušek, Markéta Tesařová, Igor Adameyko, Josef Jaroš, Marketa Kaucka, Jozef Kaiser, David Škaroupka, Tomáš Zikmund |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Reverse engineering Multi-modality systems Computerized Tomography (CT) and Computed Radiography (CR) Computer science business.industry Micro computed tomography Biological objects 3D printing Image reconstruction in medical imaging computer.software_genre Visualization 03 medical and health sciences 030104 developmental biology 0302 clinical medicine business Instrumentation Nasal capsule computer 030217 neurology & neurosurgery Mathematical Physics Biomedical engineering |
| Zdroj: | Journal of Instrumentation. 2016, vol. 11, issue 3, p. 1-11. |
| ISSN: | 1748-0221 |
| Popis: | Imaging of increasingly complex cartilage in vertebrate embryos is one of the key tasks of developmental biology. This is especially important to study shape-organizing processes during initial skeletal formation and growth. Advanced imaging techniques that are reflecting biological needs give a powerful impulse to push the boundaries of biological visualization. Recently, techniques for contrasting tissues and organs have improved considerably, extending traditional 2D imaging approaches to 3D . X-ray micro computed tomography (μCT), which allows 3D imaging of biological objects including their internal structures with a resolution in the micrometer range, in combination with contrasting techniques seems to be the most suitable approach for non-destructive imaging of embryonic developing cartilage. Despite there are many software-based ways for visualization of 3D data sets, having a real solid model of the studied object might give novel opportunities to fully understand the shape-organizing processes in the developing body. In this feasibility study we demonstrated the full procedure of creating a real 3D object of mouse embryo nasal capsule, i.e. the staining, the μCT scanning combined by the advanced data processing and the 3D printing. |
| Databáze: | OpenAIRE |
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