Primary Peripheral T-Cell Lymphoma of the Central Nervous System
| Autor: | U. Blömer, L. Dörner, E. Melnikowa, Andreas M. Stark, Hubertus Maximilian Mehdorn, M. Tiemann |
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| Rok vydání: | 2004 |
| Předmět: |
Male
Pathology medicine.medical_specialty Stereotactic biopsy Open biopsy Biopsy medicine.medical_treatment Brain Edema Lymphoma T-Cell Central Nervous System Neoplasms Fatal Outcome medicine Humans Cerebral Hemorrhage Chemotherapy medicine.diagnostic_test business.industry Brain biopsy Primary central nervous system lymphoma Magnetic resonance imaging Middle Aged medicine.disease Immunohistochemistry Magnetic Resonance Imaging Peripheral T-cell lymphoma Lymphoma Radiography Surgery Neurology (clinical) business |
| Zdroj: | Zentralblatt für Neurochirurgie. 65:191-194 |
| ISSN: | 1438-9746 0044-4251 |
| Popis: | UNLABELLED A 47-year-old man was admitted to our hospital with a nine-week history of visual disturbance, headache, disorientation and facial nerve palsy. Serial cranial magnetic resonance imaging (MRI) revealed progressive bilateral occipital edema with hemorrhage and meningeal involvement. There were no hints of hereditary or acquired immunodeficiency. Laboratory examination for bacterial and viral causes was negative. Open brain biopsy revealed primary central nervous system lymphoma of the extraordinary rare so-called "peripheral" T-cell type. The further course was fatal; the patient died 10 weeks after the onset of symptoms from tumor progression before planned chemotherapy could be started. CONCLUSION If primary central nervous system lymphoma (PCNSL) is suspected, brain biopsy -- either open biopsy or stereotactic biopsy -- should be performed straight away to enable a rapid start of chemotherapy and/or radiotherapy. Peripheral T-cell lymphoma was highly aggressive in this case leading to the patient's death within several weeks. |
| Databáze: | OpenAIRE |
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