Reduction of optic nerve fibers in patients with Alzheimer disease identified by laser imaging

Autor:	H. Birch, J. Y.-F. Ku, Helen V Danesh-Meyer, Stuart C Carroll, Greg D. Gamble
Rok vydání:	2006
Předmět:	Male Retinal Ganglion Cells Pathology medicine.medical_specialty genetic structures medicine.medical_treatment Nerve fiber Laser imaging Physical examination Cell Count Central nervous system disease Degenerative disease Alzheimer Disease Predictive Value of Tests Ophthalmology Optic Nerve Diseases medicine Humans In patient Reduction (orthopedic surgery) Aged Aged 80 and over Microscopy Confocal medicine.diagnostic_test business.industry Ophthalmoscopes Case-control study Optic Nerve Odds ratio medicine.disease eye diseases Scanning laser ophthalmoscopy medicine.anatomical_structure Case-Control Studies Optic nerve Female Neurology (clinical) sense organs Alzheimer's disease business Wallerian Degeneration
Zdroj:	Neurology. 67(10)
ISSN:	1526-632X
Popis:	In this case-control study, we compared the optic nerves (ONs) by clinical examination and scanning laser ophthalmoscopy (SLO) of 40 patients with Alzheimer disease (AD) and 50 controls. There was a reduction in the number of ON fibers in patients with AD, with a threefold greater odds ratio for a larger optic cup-to-disc ratio in patients with AD.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b543ad859138a14b6903e9ecc34fb881 https://pubmed.ncbi.nlm.nih.gov/17130403 Zobrazit plný text záznamu