| Autor: |
Magdalena Karbowniczek, Maciej M. Markiewski, David J. Kwiatkowski, Elizabeth P. Henske, Aristotelis Astrinidis, Maureen E. Murphy, Che-Pei Kung, Shanawaz Ghouse, Surya Kumari Vadrevu, Sasikanth Manne, Hossein Mansouri, Santosh Bonala, Bhaumik Patel, Jun-Hung Cho |
| Rok vydání: |
2023 |
| DOI: |
10.1158/1541-7786.22515768.v1 |
| Popis: |
S1. Expression of hamartin and p53 in mice. S2. CRISPR-Cas9 mediated editing of TP53 codon 72 in angiomyolipoma cells and the impact of R72 on Notch/Nodal axis. S3. Overexpression of Nodal in LAM. S4. Overexpression of Nodal in TSC-associated renal tumors. S5. R72 increases migration of angiomyolipoma cells. Supplementary Table S1. The frequency of TP53 codon 72 germline polymorphism in TSC and LAM patients. Supplementary Table S2. The frequency of TP53 R72 codon polymorphism in TSC and sporadic angiomyolipoma and TSC-associated RCC. Supplementary Table S3. The number of experimental mice used in study. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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