No increase in breast cancer risk in Japanese women taking oral contraceptives: a case-control study investigating reproductive, menstrual and familial risk factors for breast cancer
| Autor: | Miho Ichida, Akemi Kataoka, Tetsuya Taguchi, Ruriko Tsushima |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Cancer Research medicine.medical_specialty Time Factors Epidemiology Population Breast Neoplasms Lower risk Young Adult Breast cancer Risk Factors Medicine Humans Genetic Predisposition to Disease Family history Young adult education Prospective cohort study Aged Gynecology education.field_of_study business.industry Obstetrics Reproduction Public Health Environmental and Occupational Health Case-control study Middle Aged medicine.disease Prognosis Menstruation Oncology Case-Control Studies Female business Breast feeding Contraceptives Oral Follow-Up Studies |
| Zdroj: | Asian Pacific journal of cancer prevention : APJCP. 16(9) |
| ISSN: | 2476-762X |
| Popis: | Background: Low-dose oral contraceptives (OC) were approved by the Japanese Ministry of Health, Labor and Welfare in 1999, yet despite their contraceptive and non-contraceptive health benefits, only 5% of the target population use them. Fear of increased cancer risk, particularly breast cancer, is one reason for this. Due to low OC uptake and low screening participation, a paucity of data is available on the risk of OC use and breast cancer in Japanese women. The present study investigated OC use and breast cancer risk, as well as menstrual, reproductive and family factors. Materials and Methods: This was a clinic-based case-control study of women aged 20-69yrs who had undergone breast screening between January 2007 and December 2013 in central Tokyo. In all, 28.8% of the participants had experience with OC use. Cases were 155 women with a pathologically confirmed diagnosis of breast cancer. Controls were the remaining 12,333 women. Results: Increased age was a significant risk factor for breast cancer (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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