Effectiveness of histology and cytology on musculoskeletal tumor diagnosis
| Autor: | Roberto José Vieira de Mello, Jairo de Andrade Lima, Marcelo Parente Oliveira, george rocha ferreira, túlio paes de medeiros lima, Pablo Moura de Andrade Lima |
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| Rok vydání: | 2014 |
| Předmět: |
Pathology
medicine.medical_specialty Youden's J statistic Musculoskeletal tumor Physical Therapy Sports Therapy and Rehabilitation Surgical specimen Cytology Positive predicative value Medicine Orthopedics and Sports Medicine Orthopedic surgery business.industry Rehabilitation Bone neoplasms Sarcoma Histology medicine.disease Biopsy needle Predictive value Original Article Radiology business RD701-811 |
| Zdroj: | Acta Ortopédica Brasileira v.22 n.3 2014 Acta Ortopédica Brasileira Sociedade Brasileira de Ortopedia e Traumatologia (SBOT) instacron:SBOT Acta Ortopédica Brasileira, Vol 22, Iss 3, Pp 132-135 (2014) Acta Ortopédica Brasileira, Volume: 22, Issue: 3, Pages: 132-135, Published: 2014 Acta Ortopedica Brasileira |
| ISSN: | 1413-7852 |
| DOI: | 10.1590/1413-78522014220300440 |
| Popis: | OBJECTIVE: To compare cytology and histology on the diagnosis of musculoskeletal neoplasms. METHOD: Fifty eight cases available to evaluation were analyzed both by cytology and histology. The results of the biopsies studied by histology and cytology were compared to the results obtained on the surgical specimen or immunohistochemistry. We determined the percentage of correct results, sensitivity, specificity, positive and negative predictive values and accuracy of each method. RESULTS: Twelve per cent of biopsies were inconclusive by cytology. The percentage of correct diagnosis was 70.7% and 81% (p=.179), the ability to differentiate benign lesions from malignant ones was 84.5% and 93.1% (p=0.18) respectively, for cytology and histology. Cytology showed sensitivity of 87.8%, specificity of 76.5%, positive predictive value of 90%, negative predictive value of 72% and accuracy 84.5%. Histology showed sensitivity of 90.2%, specificity of 100%, positive predictive value of 100%, negative predictive value of 81% and accuracy of 93.1%. The Youden index for cytology was 64.3% and for histology it was 90.2%. CONCLUSION: Despite promising, cytology obtained by thin needle aspiration is less accurate and reliable than the histological evaluation on musculoskeletal tumors diagnosis. Level of Evidence II, Diagnostic Studies. |
| Databáze: | OpenAIRE |
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