Inconsistencies of the Disease Activity Assessment Tools for Psoriatic Arthritis: Challenges to Rheumatologists
| Autor: | Mustafa Çaliş, Murat Toprak, Halise Hande Gezer, Hatice Bodur, Cevriye Mülkoğlu, Fikriye Figen Ayhan, Nihan Cuzdan, Oznur Kutluk, Ajda Bal, Nilay Sahin, Gizem Cengiz, Tiraje Tuncer, İbrahim Tekeoğlu, Sena Tolu, Ilknur Albayrak Gezer, Betul Sargin, Meltem Alkan Melikoglu, Sami Hizmetli, Nesrin Şen, Sevtap Acer Kasman, Hakan Alkan, Dilek Keskin, Kevser Gok, Yaşar Keskin, Gul Devrimsel, Erhan Capkin, Ayhan Kamanli, Erkan Kilic, Okan Küçükakkaş, Hilal Ecesoy, Mehmet Tuncay Duruöz, Ömer Faruk Şendur, Ozan Volkan Yurdakul, Hatice Reşorlu, İsmihan Sunar, Merve Baykul, Kemal Nas |
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| Přispěvatelé: | KESKİN, Yaşar |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Male
Disease physical examination Severity of Illness Index middle aged Health Assessment Questionnaire rheumatologist skin and connective tissue diseases disease activity score Disease Activity in Psoriatic Arthritis adult Fibromyalgia Rapid Screening Tool Remission Induction Swollen joints anxiety Peripheral Hospital Anxiety and Depression Scale female low disease activity Treatment Outcome Antirheumatic Agents depression joint swelling medicine.symptom enthesopathy musculoskeletal diseases medicine.medical_specialty dactylitis Remission Psoriatic Arthritis Challenges to Rheumatologists.- Joint bone spine ss.105296 2021 [Gezer H. H. Duruöz M. T. Nas K. Kılıç E. Sargın B. Kasman S. A. Alkan H. Şahin N. Cengiz G. Cüzdan N. et al. -Inconsistencies of the Disease Activity Assessment Tools for Psoriatic Arthritis] prostate specific antigen patient-reported outcome Article rate of remission Disease activity Psoriatic arthritis Rheumatology Internal medicine medicine diverse activity scale DAS28 Humans In patient controlled study human Disease Activity clinical assessment tool Composite Index business.industry enthesitis Arthritis Psoriatic Enthesitis visual analog scale clinical assessment very low disease activity Prostate-Specific Antigen medicine.disease major clinical study antirheumatic agent minimal disease activity fatigue disease duration Rheumatologists business Rheumatism |
| Popis: | Objective: Currently, concerning the evaluation of psoriatic arthritis (PsA), there is no agreement on a standardized composite index for disease activity that includes all relevant domains. The present study sought to assess the rates of remission (REM)/low disease activity (LDA) and disease states [minimal disease activity (MDA), very low disease activity (VLDA)] as defined by diverse activity scales (DAPSA, DAS28-ESR) in an attempt to display discrepancies across these assessment tools for peripheral PsA. Methods: The study involved 758 patients (496 females, 262 males; mean age 47,1 years) with peripheral PsA who were registered to the Turkish League Against Rheumatism (TLAR) Network. The patients were assessed using the DAS28-ESR, DAPSA, MDA, and VLDA. The overall yield of each scale was assessed in identifying REM and LDA. The presence or absence of swollen joints was separately analysed. Results: The median disease duration was 4 years (range 0-44 years). According to DAPSA and DAS28-ESR, REM was achieved in 6.9% and 19.5% of the patients, respectively. The rates of MDA and VLDA were 16% and 2.9%, respectively. Despite the absence of swollen joints, a significant portion of patients were not considered to be in REM (296 (39.1%) patients with DAS28-ESR, 364 (48%) with DAPSA, and 394 (52%) with VLDA). Conclusion: Patients with peripheral PsA may be assigned to diverse disease activity levels when assessed with the DAS28-ESR, DAPSA, MDA and VLDA, which would inevitably have clinical implications. In patients with PsA a holistic approach seems to be necessary which includes other domains apart from joint involvement, such as skin involvement, enthesitis, spinal involvement, and patient-reported outcomes. © 2021 Société française de rhumatologie |
| Databáze: | OpenAIRE |
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