Statistics on mortality following acute myocardial infarction in 842 897 Europeans

Autor: Chris P Gale, Bertil Lindahl, Tomas Jernberg, O A Alabas, Marlous Hall, Mark J. Rutherford, Keith A.A. Fox, Robert West, Harry Hemingway, Adam Timmis, Mar Pujades-Rodriguez
Rok vydání: 2019
Předmět:
Male
Time Factors
Heart disease
Physiology
medicine.medical_treatment
030204 cardiovascular system & hematology
0302 clinical medicine
Risk Factors
Cause of Death
Myocardial Revascularization
Prevalence
Registries
UK
030212 general & internal medicine
Myocardial infarction
Practice Patterns
Physicians'

Non-ST Elevated Myocardial Infarction
Aged
80 and over

education.field_of_study
Aspirin
Middle Aged
Treatment Outcome
MINAP
Practice Guidelines as Topic
SWEDEHEART
Female
Guideline Adherence
Cardiology and Cardiovascular Medicine
medicine.drug
Adult
medicine.medical_specialty
Adolescent
Population
Acute myocardial infarction
Revascularization
Young Adult
03 medical and health sciences
Case mix index
Physiology (medical)
Internal medicine
medicine
Hospital discharge
Humans
Healthcare Disparities
Mortality
education
Aged
Sweden
business.industry
Cardiovascular Agents
medicine.disease
United Kingdom
Confidence interval
ST Elevation Myocardial Infarction
business
Zdroj: Alabas, O A, Jernberg, T, Pujades-Rodriguez, M, Rutherford, M J, West, R M, Hall, M, Timmis, A, Lindahl, B, Fox, K A A, Hemingway, H & Gale, C P 2020, ' Statistics on mortality following acute myocardial infarction in 842 897 Europeans ', Cardiovascular research, vol. 116, no. 1, pp. 149-157 . https://doi.org/10.1093/cvr/cvz197
ISSN: 1755-3245
0008-6363
DOI: 10.1093/cvr/cvz197
Popis: Aims To compare ST-segment elevation myocardial infarction (STEMI) and non-STEMI (NSTEMI) mortality between Sweden and the UK, adjusting for background population rates of expected death, case mix, and treatments. Methods and results National data were collected from hospitals in Sweden [n = 73 hospitals, 180 368 patients, Swedish Web-system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies (SWEDEHEART)] and the UK [n = 247, 662 529 patients, Myocardial Ischaemia National Audit Project (MINAP)] between 2003 and 2013. There were lower rates of revascularization [STEMI (43.8% vs. 74.9%); NSTEMI (27.5% vs. 43.6%)] and pharmacotherapies at time of hospital discharge including [aspirin (82.9% vs. 90.2%) and (79.9% vs. 88.0%), β-blockers (73.4% vs. 86.4%) and (65.3% vs. 85.1%)] in the UK compared with Sweden, respectively. Standardized net probability of death (NPD) between admission and 1 month was higher in the UK for STEMI [8.0 (95% confidence interval 7.4–8.5) vs. 6.7 (6.5–6.9)] and NSTEMI [6.8 (6.4–7.2) vs. 4.9 (4.7–5.0)]. Between 6 months and 1 year and more than 1 year, NPD remained higher in the UK for NSTEMI [2.9 (2.5–3.3) vs. 2.3 (2.2–2.5)] and [21.4 (20.0–22.8) vs. 18.3 (17.6–19.0)], but was similar for STEMI [0.7 (0.4–1.0) vs. 0.9 (0.7–1.0)] and [8.4 (6.7–10.1) vs. 8.3 (7.5–9.1)]. Conclusion Short-term mortality following STEMI and NSTEMI was higher in the UK compared with Sweden. Mid- and longer-term mortality remained higher in the UK for NSTEMI but was similar for STEMI. Differences in mortality may be due to differential use of guideline-indicated treatments.
Databáze: OpenAIRE