Effects of methylprednisolone use on viral genomic nucleic acid negative conversion and CT imaging lesion absorption in COVID‐19 patients under 50 years old
Autor: | Yuan Gong, Zhu Jin, Shixiong Chen, Baoan Gao, Li Guan, Guang-Ming Xiang |
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Rok vydání: | 2020 |
Předmět: |
Adult
Male medicine.medical_specialty Coronavirus disease 2019 (COVID-19) Absorption (skin) Methylprednisolone Gastroenterology Virus Lesion 03 medical and health sciences 0302 clinical medicine virus nucleic acid Adrenal Cortex Hormones COVID‐19 Virology Internal medicine medicine Humans 030212 general & internal medicine Lung Research Articles Retrospective Studies treatment SARS-CoV-2 business.industry COVID-19 Genomics Middle Aged medicine.disease COVID-19 Drug Treatment Treatment Outcome Infectious Diseases CT image lesion Viral pneumonia Disease Progression Nucleic acid Female 030211 gastroenterology & hepatology medicine.symptom Ct imaging Tomography X-Ray Computed business Research Article medicine.drug |
Zdroj: | Journal of Medical Virology |
ISSN: | 1096-9071 0146-6615 |
Popis: | The use of corticosteroids has been controversial in viral pneumonia. In most cases, application of methylprednisolone in severe and critical viral pneumonia patients can quickly alleviate the symptoms of dyspnea and prevent disease progression. However, some scholars have confirmed that corticosteroids delayed the body's clearance of the virus. In our retrospective non‐randomised study, 34 patients under 50 years old and diagnosed with coronavirus disease 2019 (COVID‐19) were included, according to given methylprednisolone treatment (n = 18) or not (n = 16), they were separated into 2 groups. By comparing the clinical data we concluded that corticosteroids therapy can effectively release COVID‐19 symptoms such as persistent fever and difficult breathing, improve oxygenation and prevent disease progression. However, it can prolong the negative conversion of nucleic acids. This article is protected by copyright. All rights reserved. |
Databáze: | OpenAIRE |
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