Bispidine as a helix inducing scaffold: examples of helically folded linear peptides

Autor:	Srinivas Chinthalapalli, Ram P. Verma, Ashutosh Shandilya, M. V. S. Gopalakrishna, M. B. Bijesh, V. Haridas, Sandhya Sadanandan
Rok vydání:	2013
Předmět:	chemistry.chemical_classification Scaffold Proline Right handed Chemistry Stereochemistry Circular Dichroism Metals and Alloys Solid-state Hydrogen Bonding Stereoisomerism Peptide General Chemistry Bridged Bicyclo Compounds Heterocyclic Crystallography X-Ray Protein Structure Secondary Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials Materials Chemistry Ceramics and Composites Peptides Alpha helix
Zdroj:	Chemical Communications. 49:10980
ISSN:	1364-548X 1359-7345
DOI:	10.1039/c3cc45649h
Popis:	We designed and synthesized bispidine-anchored peptides and showed that these peptides as small as B3 (containing four chiral α-amino acid residues) adopt a right handed helical conformation. Bispidine anchored linear peptide B3 adopts a helical conformation in solution and in the solid state.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b52e9f5d3f926fb1eb4847f270ff6baa https://doi.org/10.1039/c3cc45649h Zobrazit plný text záznamu