Effects of Okadaic Acid on Embryonic Development of the Starfish Asterina pectinifera
| Autor: | Yoshihiro Ozaki, Daisuke Uemura, Yasunori Ooe, Masaki Shioda, Takahiko Shimizu, Toshihiko Kasahara, Noboru Kajiyama, Susumu Ikegami |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
biology
Organic Chemistry Starfish Embryogenesis Acid phosphatase Embryo General Medicine Okadaic acid Blastomere biology.organism_classification Blastula Cleavage (embryo) Applied Microbiology and Biotechnology Biochemistry Analytical Chemistry Cell biology chemistry.chemical_compound chemistry embryonic structures biology.protein Molecular Biology Biotechnology |
| Zdroj: | Bioscience, biotechnology, and biochemistry. 56(7) |
| ISSN: | 0916-8451 |
| Popis: | The effects of okadaic acid, an inhibitor of protein phosphatases types 1 and 2A, from the sponge Halichondria okadai Kadota, on the embryonic development of the starfish Asterina pectinifera, were investigated. When cultured in okadaic acid from fertilization, the embryo divided synchronously without any abnormalities such as lysis, swelling or morphological changes different from control embryos up to the 32-cell stage. However, okadaic acid prevented development before the onset of blastulation. Cytological examination showed that chromosomes condensed but did not align in a plane in the mitotic apparatus in each of the blastomeres of the treated embryo at the sixth cleavage, suggesting that this was the root cause of the arrest of further development. |
| Databáze: | OpenAIRE |
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