Effect of PEEP on lung water content in experimental noncardiogenic pulmonary edema
| Autor: | Bernard L. Bradley, David L. Rice, Warren C. Miller, Kenneth M. Unger |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
medicine.medical_specialty
Pulmonary Edema Critical Care and Intensive Care Medicine Positive-Pressure Respiration Dogs Body Water In vivo Internal medicine Animals Medicine Lung Intermittent Positive-Pressure Breathing Pyrrolizidine Alkaloids Monocrotaline business.industry Oxygenation respiratory system Pulmonary edema medicine.disease respiratory tract diseases Oxygen Lung water Intermittent positive pressure breathing Breathing Cardiology business |
| Zdroj: | Critical Care Medicine. 9:7-9 |
| ISSN: | 0090-3493 |
| DOI: | 10.1097/00003246-198101000-00002 |
| Popis: | After administration of monocrotaline to dogs to produce noncardiogenic pulmonary edema, one-half of the animals (controls) were treated with intermittent positive pressure breathing (IPPV), and one-half with that ventilation plus the addition of 10 cm H2O of positive end-expiratory pressure (PEEP). After 6 h, the animals treated with PEEP demonstrated significantly better arterial oxygenation and reduced AaDO2, but lung water, quantitated either postmortem or in vivo by indicator-dilution techniques, was no less than controls. Although PEEP improves gas exchange, it fails to modify the degree of pulmonary edema represent. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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