Low-cost, flexible, disinfectant-free and regular-array three-dimensional nanopyramid antibacterial films for clinical applications
| Autor: | Xin Li, Kwong Hoi Tsui, Jiang Chen, Siu-Fung Leung, Wing Yi Chak, Zhiyong Fan, James K.H. Tsoi, Tang Lei, Gary S.P. Cheung, Chengfei Zhang |
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| Rok vydání: | 2018 |
| Předmět: |
Nanostructure
Materials science Scanning electron microscope Confocal Population Nanotechnology 02 engineering and technology 010402 general chemistry 01 natural sciences chemistry.chemical_compound Microscopy Escherichia coli General Materials Science education education.field_of_study Microscopy Confocal 021001 nanoscience & nanotechnology Aspect ratio (image) 0104 chemical sciences Anti-Bacterial Agents Nanostructures chemistry Microscopy Electron Scanning Regular array Polystyrene 0210 nano-technology Disinfectants |
| Zdroj: | Nanoscale. 10(22) |
| ISSN: | 2040-3372 |
| Popis: | In this work, a low-cost, scalable and highly repeatable approach was developed to prepare polystyrene films with three-dimensional nanopyramids on the surface. The nanopyramids have a tunable aspect ratio and more importantly, their anti-bacterial performance has been systematically studied. The effectiveness of the nanopyramids on E. coli growth inhibition and the role of the nanostructure aspect ratio were carefully studied through scanning electron microscopy and confocal laser scanning microscopy. The results showed an excellent antibacterial performance with more than 90% reduction in the E. coli population in all nanopyramid samples after a 168 h prolonged incubation time. The nanopyramid film developed here can be used for clinical and commercial applications to prevent the growth of pathogenic bacteria on various surfaces. |
| Databáze: | OpenAIRE |
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