Mass spectrometric detection of and similarities between 1-androgens
| Autor: | Dirk Courtheyn, W. Gillis, K. Verheyden, Herlinde Noppe, H.F. De Brabander, P. Vanthemsche, Virginie Mortier, M Vandewiele, B. Le Bizec |
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| Rok vydání: | 2007 |
| Předmět: |
Androstenediol
Chromatography Gas Weight Lifting Anabolism medicine.medical_treatment Administration Oral 1-Testosterone Mass spectrometry Tandem mass spectrometry Biochemistry Gas Chromatography-Mass Spectrometry Mass Spectrometry Analytical Chemistry Steroid chemistry.chemical_compound Anabolic Agents medicine Environmental Chemistry Testosterone Chromatography High Pressure Liquid Spectroscopy Doping in Sports Chromatography Mass spectrometric Substance Abuse Detection Models Chemical chemistry Androgens Steroids Gas chromatography Chromatography Liquid |
| Zdroj: | Analytica Chimica Acta. 586:57-72 |
| ISSN: | 0003-2670 |
| Popis: | Regularly new anabolic steroids appear on the black market. In most cases these substances are marketed on websites or are confiscated during inspections. 1,(5alpha)-Androstene-17beta-ol-3-one, also known as 1-testosterone, is one of these substances presented to body-builders as a nutritional supplement or a pro-hormone. 1-Testosterone closely resembles the natural hormone testosterone except for a 1,2-double bound instead of a 4,5-double bound. 1-Androstene-3beta,17beta-diol is transformed into 1-testosterone after oral administration. 1-Testosterone, 1-androstene-3beta,17beta-diol and some other related 'new' anabolic steroids were studied with gas chromatography coupled to mass spectrometry (GC-MS) and Liquid chromatography coupled to tandem mass spectrometry (LC-MS2) methods. Similarities in spectra to known analytes, which may lead to pitfalls in the interpretation of the derivatised analytes, are discussed. |
| Databáze: | OpenAIRE |
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