| Autor: |
Yanan Zhang, Zhaozhou Liu, Shuangshuang Li, Shen Yang, Jiawei Zhao, Ting Yang, Siqi Li, Yongwei Chen, Weihong Guo, Dawei Hou, Yingzi Li, Jinshi Huang |
| Rok vydání: |
2022 |
| Předmět: |
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| DOI: |
10.21203/rs.3.rs-1673890/v2 |
| Popis: |
Objective To evaluate the safety and efficacy of the transanal endorectal pull-through (TEPT) and the long-term outcomes in newborns with HD. Methods A total of 229 newborns with HD underwent one-stage TEPT between 2007 and 2020, and the diagnoses were confirmed by rectal biopsy. The perioperative clinical course for all patients was reviewed, and the postoperative short- and long-term outcomes were assessed. Results A total of 229 neonates (187 male and 42 female) had a median age at TEPT of 17 days (range, 6–28 days). Sixty-eight patients (29.7%) underwent TEPT combined with an abdominal approach or laparoscopy. Early postoperative complications were documented in 26 patients (11.4%). The follow-up period in the remaining 165 children ranged from 1.2 to 14.0 years (median, 5.0 years), and late postoperative complications were noted in 6 patients (3.6%). A total of 106 of the patients older than four years old took part in an interview about bowel function, and 85 patients (80.2%) had a bowel function scores (BFS) ≥ 18. Conclusion TEPT is effective and safe in the treatment of neonatal HD and presents with a low rate of complications and an acceptable outcome. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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