Preliminary results of femtosecond laser-assisted descemet stripping endothelial keratoplasty

Autor: Cathariena A. Eggink, Fred Hendrikse, Robert-Jan Wijdh, Rudy M.M.A. Nuijts, Wilhelmina J. Rijneveld, Hugo van Cleynenbreugel, Yanny Y. Y. Cheng, Elisabeth Pels, Gabriel van Rij
Přispěvatelé: Ophthalmology, Netherlands Institute for Neuroscience (NIN)
Rok vydání: 2008
Předmět:
Graft Rejection
Male
Visual acuity
genetic structures
Corneal Surgery
Laser
DLEK
Visual Acuity
Glaucoma
Corneal Diseases
Corneal Transplantation
Cornea
VISUAL-ACUITY
Neurosensory disorders [UMCN 3.3]
Prospective Studies
SURGICAL TECHNIQUE
medicine.diagnostic_test
Endothelium
Corneal
Graft Survival
MICROSCOPY
Middle Aged
Corneal topography
medicine.anatomical_structure
Treatment Outcome
EYE BANK EYES
Evaluation Studies as Topic
Descemet Stripping Endothelial Keratoplasty
Female
medicine.symptom
FUTURE-DIRECTIONS
medicine.medical_specialty
POSTERIOR LAMELLAR KERATOPLASTY
Fuchs Endothelial Dystrophy
Astigmatism
Risk Assessment
Statistics
Nonparametric
Ophthalmology
medicine
Humans
Descemet Membrane
Aged
Probability
business.industry
TRANSPLANTATION
Fuchs' Endothelial Dystrophy
medicine.disease
VIABILITY
eye diseases
Surgery
Transplantation
DONOR TISSUE
sense organs
business
Follow-Up Studies
Zdroj: Archives of Ophthalmology, 126(10), 1351-1356. American Medical Association
Archives of Ophthalmology, 126, 1351-6
Archives of Ophthalmology, 126, 1351-1356. American Medical Association
ARCHIVES OF OPHTHALMOLOGY, 126(10), 1351-1356. AMER MEDICAL ASSOC
Archives of Ophthalmology, 126, 10, pp. 1351-6
ISSN: 0003-9950
DOI: 10.1001/archopht.126.10.1351
Popis: Contains fulltext : 71383.pdf (Publisher’s version ) (Closed access) OBJECTIVE: To evaluate the preliminary visual results of femtosecond laser-assisted Descemet stripping endothelial keratoplasty (FS-DSEK). METHODS: We prospectively analyzed results of 20 consecutive patients with Fuchs endothelial dystrophy or aphakic/pseudophakic bullous keratopathy who underwent FS-DSEK. Best spectacle-corrected visual acuity (BSCVA), refraction, corneal topography, and endothelial cell density were measured preoperatively and 3 and 6 months after FS-DSEK. Corneal thickness was measured using an optical coherence tomography technique. RESULTS: The average BSCVA of 11 eyes with normal visual potential significantly improved from 20/110 +/- 4 lines to 20/57 +/- 1 line at 6 months (P < .007). At 6 months, the mean (SD) hyperopic shift was 2.24 (2.3) diopters (D). Preoperative and 6 months postoperative refractive astigmatism were -0.75 (0.9) D and -1.58 (1.1) D (P = .01), but the topographic astigmatism did not change postoperatively (P = .95). Mean (SD) endothelial cell density at 6 months was 1368 (425) cells/mm(2). There was a persistent deswelling of the graft up to 3 months postoperatively. Complications included graft dislocations requiring repositioning (20%), pupillary block glaucoma (5%), epithelial ingrowth (5%), and primary graft failure (5%). CONCLUSIONS: Femtosecond laser-assisted Descemet stripping endothelial keratoplasty was effective in treating endothelial failure with minimal induced refractive astigmatism, limited improvement of BSCVA, and induction of a hyperopic shift. Endothelial cell count and dislocation rate were significant, which may be related to the surgical technique.
Databáze: OpenAIRE
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