Bone Marrow Metastasis of Rhabdomyosarcoma Mimicking Acute Leukemia: A Case Report and Review of the Literature
| Autor: | Keijiro Sato, Takehiko Kirihara, Mayumi Ueno, Wataru Takeda, Masahiko Sumi, Yuka Aida, Yuki Hiroshima, Ikuo Shimizu, Taro Kurihara, Masahide Watanabe, Toshimitsu Ueki, Hikaru Kobayashi, Naoaki Ichikawa |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Nasal cavity Pathology medicine.medical_specialty medicine.medical_treatment Diagnosis Differential Bone Marrow hemic and lymphatic diseases Antineoplastic Combined Chemotherapy Protocols Rhabdomyosarcoma Internal Medicine medicine Humans Chemotherapy Acute leukemia Leukemia business.industry General Medicine medicine.disease Thrombocytopenia Radiation therapy Treatment Outcome medicine.anatomical_structure Bone marrow neoplasm Female Bone marrow Bone Marrow Neoplasms business |
| Zdroj: | Internal Medicine. 54:643-650 |
| ISSN: | 1349-7235 0918-2918 |
| DOI: | 10.2169/internalmedicine.54.2473 |
| Popis: | Bone marrow metastasis of rhabdomyosarcoma has been reported to be difficult to distinguish from acute leukemia. We herein describe a case of rhabdomyosarcoma with bone marrow metastasis mimicking acute lymphoblastic leukemia. A 29-year-old woman was admitted with thrombocytopenia, blast-like cells in the peripheral blood and a coagulation disorder. Bone marrow aspirates showed 94.8% blast-like cell infiltration (CD45(-), myeloperoxidase(-), and CD56(+)), and CT scan revealed the presence of an infiltrating mass in the nasal cavity. Based on a biopsy of the nasal cavity, the patient was diagnosed with rhabdomyosarcoma exhibiting bone marrow metastasis. She received chemotherapy, followed by radiation therapy, and has since remained alive for 26 months, as of the last follow-up. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|