A single vaccination with an inactivated hepatitis A liposome vaccine induces protective antibodies after only two weeks
| Autor: | H. Drechsler, S. Brantschen, R. Berger, Max Just, R. Glück |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Adult
Male Viral Hepatitis Vaccines Vaccination schedule medicine.medical_treatment Hepatitis A vaccine Injections Intramuscular medicine Humans Hepatitis Antibodies Seroconversion Immunization Schedule Hepatitis A Vaccines Reactogenicity General Veterinary General Immunology and Microbiology business.industry Immunogenicity Vaccination Public Health Environmental and Occupational Health Hepatitis A medicine.disease Virology Infectious Diseases Vaccines Inactivated Immunology Liposomes Molecular Medicine Female business Adjuvant |
| Zdroj: | Vaccine. 10(11) |
| ISSN: | 0264-410X |
| Popis: | In the near future an inactivated hepatitis A vaccine will be commercially available. The recommended vaccination schedule will include at least two vaccinations 1 month apart. Giving two doses of vaccine on the same day in one injection results in protection after 2–4 weeks dependent on the adjuvant used. Hepatitis A virus incorporated into liposomes proved to be a suitable formulation in term of rapid seroconversion, high level of mean antibody content and low reactogenicity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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