Crystal structures of disordered Z-type helices
| Autor: | A. Thirugnanasambandam, S. Karthik, Namasivayam Gautham, Pradeep K. Mandal |
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| Rok vydání: | 2018 |
| Předmět: |
Models
Molecular Left handed Base Sequence 010405 organic chemistry Chemistry DNA General Medicine Crystal structure Type (model theory) Crystallography X-Ray 010402 general chemistry 01 natural sciences Biochemistry 0104 chemical sciences Crystallography Pyrimidines Purines X-ray crystallography Genetics Nucleic Acid Conformation Molecular Medicine Crystallization Databases Nucleic Acid Sequence (medicine) |
| Zdroj: | Nucleosides, Nucleotides & Nucleic Acids. 38:279-293 |
| ISSN: | 1532-2335 1525-7770 |
| Popis: | The X-ray crystal structures of a decamer sequence d(CGCGTACGCG)2 and a tetradecamer sequence d(CGCGCGTACGCGCG)2 are presented here. Both sequences are alternating pyrimidine-purine repeat sequences and they form disordered, pseudo-continuous left handed Z-type helices. They demonstrate interesting variants of the 'bundles of columns of helices' mode of packing. |
| Databáze: | OpenAIRE |
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