Liver perfusion with dynamic multidetector-row computed tomography as an objective method to evaluate the efficacy of chemotherapy in patients with colorectal cancer
| Autor: | Markus Juchems, Eckhart Fröhlich, Hans-Jürgen Brambs, Wolfgang Heinz, Sandra Pauls, Stefan Schmidt, Andreas Gabelmann |
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| Rok vydání: | 2009 |
| Předmět: |
Male
Liver perfusion medicine.medical_specialty Colorectal cancer Perfusion Imaging medicine.medical_treatment Antineoplastic Agents Computed tomography medicine Humans Radiology Nuclear Medicine and imaging In patient Aged Tumor marker Chemotherapy Neovascularization Pathologic medicine.diagnostic_test business.industry Liver Neoplasms Cancer Middle Aged medicine.disease Treatment Outcome Liver Female Radiology Tomography X-Ray Computed business Perfusion |
| Zdroj: | Clinical Imaging. 33:289-294 |
| ISSN: | 0899-7071 |
| DOI: | 10.1016/j.clinimag.2008.10.030 |
| Popis: | A total of 24 liver metastases of colorectal cancer were evaluated by dynamic multiphasic CT. Under chemotherapy, follow-up examinations were performed every 3 months. The tumor marker CEA before vs. after chemotherapy correlated with the mean contrast enhancement within the margin of metastases. The total size of metastases correlated with the size of central necrosis as well as with the size of marginal contrast enhancement. CT is able to quantify perfusion and local activity of liver metastases to determine the efficacy of chemotherapy. |
| Databáze: | OpenAIRE |
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