Integrated morphologic and functional assessment of the aortic root after different tissue valve root replacement procedures

Autor: Ismail El-Hamamsy, Ryo Torii, Xiao Yun Xu, Sonya V. Babu-Narayan, Raad H. Mohiaddin, Magdi H. Yacoub, Mohamed Donya, Philip J. Kilner, Michael Ibrahim
Rok vydání: 2012
Předmět:
Zdroj: The Journal of Thoracic and Cardiovascular Surgery. 143(6):1422-1428.e2
ISSN: 0022-5223
DOI: 10.1016/j.jtcvs.2011.12.034
Popis: ObjectivesThis study was undertaken to explore aspects of the hemodynamic function of different biologic tissue aortic valve root replacements. We set out to image and display the spatiotemporal distributions of axially directed blood velocity through the aortic root.MethodsThe flow velocities through a plane transecting the aortic root were measured by 2-dimensional cine phase-contrast magnetic resonance velocity mapping in 44 subjects: 29 patients who had undergone aortic root replacement approximately 10 years previously (13 autografts, 10 stentless xenografts, and 6 homografts) and 15 healthy control subjects. With cine as well as velocity images, aortic sinus dimensions, effective orifice area, and several velocity parameters were measured. Color-coded plots of velocity relative to the sinus cross sections and velocity-time plots were used to compare spatiotemporal distributions of velocity.ResultsPeak flow velocity was similar between the autografts (102 ± 28.0 cm/s) and control valves (119 ± 20.0 cm/s) but was higher in xenografts (167 ± 36.0 cm/s) and homografts (206 ± 91.0 cm/s). These measurements showed an inverse relationship with the effective orifice area (7.27 ± 0.20, 4.24 ± 0.81, 3.37 ± 0.32, and 3.28 ± 0.87 cm2, respectively). Autograft peak flow velocity showed no significant difference from control valve peak flow velocity, despite larger root dimensions (P
Databáze: OpenAIRE