Epidemiology of hospital-based COVID- 19 cluster in a tertiary care cancer hospital, Chennai, India 2020

Autor: Swaminathan Rajaraman, Sirshendu Chaudhuri, Manickam Ponnaiah, Nuzrath Jahan, Usha Krishnan, Sendhilkumar Muthappan, Mohankumar Raju, Girish Kumar Cp, Alby John Varghese, Parasuraman Ganeshkumar, Jegadeesan Murugesan, Mathan Karuppiah, Suganya Barani, Venktesh Vaidhyalingam, Mahalakshmi Srinivasan
Rok vydání: 2021
Předmět:
Zdroj: Clinical Epidemiology and Global Health
Clinical Epidemiology and Global Health, Vol 12, Iss, Pp 100889-(2021)
ISSN: 2452-0918
Popis: Objectives To identify risk factors associated with Coronavirus disease 2019 (COVID-19) in a Tertiary care cancer hospital-based cluster and recommend control measures. Methods We conducted tracing and confirmation among hospital and community contacts. We telephonically interviewed and abstracted information from hospital records and registers. We described the cluster by time, place and person. We conducted unmatched case-control study to compare risk factors and computed Odds Ratio (OR) and 95% confidence interval. Results We confirmed COVID-19 in 21 of 1478 tested (1.4%). Secondary attack (%) of COVID-19 among 824 contacts was higher among in-patients of block A (18), household contacts (3.4), housekeeping staff (3.3) and nurses (1.7). The cluster started on April 22 with two successive peaks five days apart and lasted until May 8. Being male, patients aged >33 years [OR = 30·7; 95% CI = 3·6 to 264], having hypertension [OR = 4·3; 95% CI = 1·1 to 16·7] or diabetes [OR = 3·8; 95% CI = 1·0 to 14·1] were associated with COVID-19. Mask compliance was poor (20%) among hospital workers. Discussion We recommended screening of all patients for diabetes and hypertension and isolation/testing of anyone with influenza-like illness for preventing COVID-19 clusters in hospital settings.
Databáze: OpenAIRE