Apical periodontitis associates with cardiovascular diseases: a cross-sectional study from Sweden

Autor: Stella Airila-Månsson, Jukka H. Meurman, Birgitta Söder, Per-Östen Söder, Tapio Nurmi, Eunice Virtanen
Přispěvatelé: Clinicum, University of Helsinki, Department of Oral and Maxillofacial Diseases, HUS Head and Neck Center
Rok vydání: 2017
Předmět:
Male
Cross-sectional study
Dentistry
030204 cardiovascular system & hematology
0302 clinical medicine
POPULATION
Univariate analysis
education.field_of_study
medicine.diagnostic_test
Middle Aged
PREVALENCE
3. Good health
Cardiovascular diseases
Population study
Female
SMOKING
ENDODONTICALLY TREATED TEETH
Research Article
BACTEREMIA
medicine.medical_specialty
Population
Physical examination
FREQUENCY
03 medical and health sciences
INFLAMMATION
Apical periodontitis
Internal medicine
medicine
Humans
Periodontitis
Systemic diseases
education
General Dentistry
Sweden
Hospital care
Analysis of Variance
Chi-Square Distribution
Periapical periodontitis
business.industry
DIABETES-MELLITUS
030206 dentistry
Odds ratio
medicine.disease
313 Dentistry
ROOT-FILLED TEETH
lcsh:RK1-715
Cross-Sectional Studies
lcsh:Dentistry
PERIAPICAL STATUS
business
Periapical Periodontitis
Zdroj: BMC Oral Health
BMC Oral Health, Vol 17, Iss 1, Pp 1-8 (2017)
ISSN: 1472-6831
DOI: 10.1186/s12903-017-0401-6
Popis: Background: Periodontal disease associates with systemic diseases but corresponding links regarding apical periodontitis (AP) are not so clear. Hence our aim was to study association between AP and the prevalence of systemic diseases in a study population from Sweden. Methods: The subjects were 150 patients from a randomly selected epidemiological sample of 1676 individuals. 120 accepted to participate and their basic and clinical examination data were available for these secondary analyses where dental radiographs were used to record signs for endodontic treatments and AP. Periapical Index and modified Total Dental Index scores were calculated from the x-rays to classify the severity of AP and dental infection burden, respectively. Demographic and hospital record data were collected from the Swedish National Statistics Center. T-test, chi-square and univariate analysis of covariance (ANCOVA) and regressions analyses were used for statistics. Results: Of the 120 patients 41% had AP and 61% had received endodontic treatments of which 52% were radiographically unsatisfactory. AP patients were older and half of them were smokers. AP and periodontitis often appeared in the same patient (32.5%). From all hospital diagnoses, cardiovascular diseases (CVD) were most common, showing 20.4% prevalence in AP patients. Regression analyses, controlled for age, gender, income, smoking and periodontitis, showed AP to associate with CVD with odds ratio 3.83 (95% confidence interval 1.18-12.40; p = 0.025). Conclusions: The results confirmed our hypothesis by showing that AP statistically associated with cardiovascular diseases. The finding that subjects with AP also often had periodontitis indicates an increased oral inflammatory burden.
Databáze: OpenAIRE
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